{"product_id":"pure-sleep-60ct","title":"Pure Sleep, 60ct","description":"\u003cp\u003ePromotes sleep quality\u003c\/p\u003e\n\u003cbr\u003e\n\u003cdiv class=\"description product-description\" data-model=\"XLite\\Model\\Product\" data-identifier=\"65736\" data-property=\"description\"\u003e\n\u003cp\u003e\u003cstrong\u003eBenefits \u0026amp; Features\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHelps your patients fall asleep, stay asleep, and wake up refreshed without morning grogginess\u003c\/li\u003e\n\u003cli\u003eImproves sleep quality, efficiency and duration with continued use\u003c\/li\u003e\n\u003cli\u003eHelps relieve occasional stress and anxiety\u003c\/li\u003e\n\u003cli\u003eSupports a healthy cortisol response\u003c\/li\u003e\n\u003cli\u003eMelatonin free\u003c\/li\u003e\n\u003cli\u003eClinically studied ashwagandha (KSM-66)\u003c\/li\u003e\n\u003cli\u003eClinically studied saffron (affron®)\u003c\/li\u003e\n\u003cli\u003eClinically studied valerian root (Sleeproot)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eIndications\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e For patients seeking support for sleep onset and\/or duration\u003c\/p\u003e\n\u003cp\u003e For patients requesting a melatonin-free product\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuggested Use\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs a dietary supplement, take 2 capsules, 30-60 minutes before bedtime.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eScience \u0026amp; Research\/Verifiable Science\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePure Sleep combines three clinically studied botanical extracts to help patients fall asleep, stay asleep and experience the restorative, restful sleep they need without morning grogginess. KSM-66 ® ashwagandha (Withania somnifera) root extract is a calming adaptogen that helps relieve occasional stress and anxiety and supports a healthy cortisol response.1, 2 Results from several randomized, placebo-controlled trials indicate that KSM-66 ® supports sleep onset, helping individuals fall asleep faster, while enhancing sleep quality and efficiency when taken continuously over several weeks.2-4 In a randomized, double blind clinical trial involving 80 adults, ashwagandha supplementation (KSM-66 ®, 300 mg twice daily) for 8 weeks led to a significant mean reduction in sleep onset latency (the time it takes to fall asleep after going to bed), sleep quality, and total sleep time.3 A 12- week randomized, double blind clinical trial demonstrated that ashwagandha (KSM-66 ®, 300 mg twice daily) improved subjective sleep parameters and mental alertness on rising, in healthy elderly subjects.4 Results from multiple clinical trials demonstrate that saffron extract (affron ®) promotes multiple aspects of restful sleep, supporting sleep onset and duration with continued use.5-7 In a randomized, double blind clinical trial involving 66 adults, saffron (affron ®, 15.5 mg per day) for 6 weeks led to significant improvements in ease of getting to sleep, sleep quality, sleep duration, and global Pittsburgh Sleep Quality Index (PSQI) scores.5 In a randomized double-blind, placebo controlled trial involving 63 healthy adults aged 18-70 with self-reported sleep concerns, saffron (affron ®, 14 mg twice daily) for 28 days led to greater improvements in Restorative Sleep Questionnaire (RSQ) total scores and the Pittsburgh Sleep Diary (PSD) sleep quality ratings compared to placebo.6 This formula also provides Sleeproot, a valerian root extract standardized to a higher potency (2% total valerenic acids) than typical extracts, that promotes sleep quality, efficiency and duration. In a randomized, double blind clinical trial involving 72 adults, Sleeproot (200 mg\/day) for 8 weeks improved overall sleep quality, reduced sleep latency, enhanced sleep efficiency, and prolonged total sleep time. Sleeproot resulted in significant improvements in mean total PSQI sleep scores and reduced sleep latency, assessed by wrist actigraphy, compared to placebo.8‡\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e Salve J, et al. Cureus 2019 Dec 25;11(12):e6466.\u003c\/p\u003e\n\u003cp\u003e Langade D, et al. Cureus 2019; 11(9): e5797.\u003c\/p\u003e\n\u003cp\u003e Langade D, et al. J Ethnopharmacol. 2021; 264: 113276.\u003c\/p\u003e\n\u003cp\u003e Kelgane SB, et al. Cureus 2020; 12(2): e7083.\u003c\/p\u003e\n\u003cp\u003e Pachikian BD, et al. Nutrients 2021 Apr 27;13(5):1473.\u003c\/p\u003e\n\u003cp\u003e Lopresti AL, et al. J Clin Sleep Med. 2020 Jun 15;16(6):937-947.\u003c\/p\u003e\n\u003cp\u003e Lopresti AL, et al. Sleep Med. 2021 Oct;86:7-18.\u003c\/p\u003e\n\u003cp\u003e Shekhar CH, et al. Adv Ther. 2024 Jan;41(1):246-261.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWarning\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNot to be taken if you are pregnant or lactating. Consult your healthcare practitioner before use if on any medication or have any health condition. Discontinue use and seek medical advice if adverse reaction occur. Product may impair ability to drive a motor vehicle or operate machinery.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eStore in a cool, dry place.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSource\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e Ashwagandha extract is derived from Withania somnifera root\u003c\/p\u003e\n\u003cp\u003e Valerian extract is derived from Valeriana officinalis root\u003c\/p\u003e\n\u003cp\u003e Theanine is derived from fermentation\u003c\/p\u003e\n\u003cp\u003e Saffron is derived from Crocus sativus stigma extract\u003c\/p\u003e\n\u003cp\u003e Ascorbyl palmitate is derived from corn dextrose fermentation and palm oil\u003c\/p\u003e\n\u003cp\u003e Hypoallergenic plant fiber is derived from pine cellulose\u003c\/p\u003e\n\u003cp\u003e Tri-magnesium citrate is derived from elemental ore and non-GMO glucose fermentation from non-GMO maize, molasses, and sugar beet or sugar cane\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/drive.google.com\/file\/d\/17mkXlBtzgBf3A5hJqq3IiA2PUIQQ_Urm\/view?usp=sharing\" rel=\"noopener noreferrer\" target=\"_blank\"\u003ePure Sleep Product Information Sheet 1\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/drive.google.com\/file\/d\/12pJdrsWDm2zLObdrVyK5MRg5JnUh-tGY\/view?usp=sharing\" rel=\"noopener noreferrer\" target=\"_blank\"\u003ePure Sleep Product Information Sheet 2\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cbr\u003e\n\u003cp\u003e\u003cstrong\u003eUnit Size:\u003c\/strong\u003e 60 capsules\u003c\/p\u003e\n\u003cbr\u003e\n\u003cp\u003e\u003cstrong\u003eIngredients\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eSupplement Facts2 capsules, 30-60 minutes before bedtime.Two (size 00) capsules contain:KSM-66 Ashwagandha® 600 mg(Withania somnifera) extract (root)Sleeproot valerian (Valeriana officinalis) extract (root) 200 mg(standardized to contain 2% valerenic acid)Suntheanine® (l-Theanine) 100 mgAffron® saffron (Crocus sativus) extract (stigma) 28 mg(standardized to contain 3.5% Lepticrosalides®)Other ingredients: vegetarian capsule (cellulose, water), hypoallergenicplant fiber (cellulose), ascorbyl palmitate, tri-magnesium citrateWARNING: Not to be taken if you are pregnant or lactating. Consult yourhealthcare practitioner before use if on any medication or have any healthcondition. Discontinue use and seek medical advice if adverse reactionsoccur. Product may impair ability to drive a motor vehicle or operatemachinery.KSM-66 Ashwagandha® is a registered trademark of Ixoreal BiomedInc.Sleeproot is a trademark of OmniActive Health Technologies Ltd.Suntheanine® is a registered trademark of Taiyo International, Inc.Affron® \u0026amp; Lepticrosalides® are trademarks owned by PharmactiveBiotech Products S.L.U.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":47461412438172,"sku":"P357","price":36.75,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0473\/2407\/0044\/files\/pure-sleep-pure-encapsulations.png?v=1787529048","url":"https:\/\/primenaturalfoods.com\/en-ae\/products\/pure-sleep-60ct","provider":"Prime Natural Foods","version":"1.0","type":"link"}