Active Folate 1000

Biologically active folate rich formula
• Helps to reduce the risk of neural tube defects (NTD) when taken daily prior to becoming pregnant and during early pregnancy
• Helps to prevent folate deficiency
• Helps the body to metabolize proteins and form red blood cells
• Provides 1,000 mcg of folate per day from Metafolin^®

Active Folate 1000 provides 1,000 mcg of folate per day from Metafolin^® – a pure, physiologically active and bioavailable form of the folate found naturally in foods.¹ Folate is primarily involved in cell division and is required for the synthesis of nucleotides and red blood cells.² Folate requirements increase during pregnancy as a result of the rise in cell division and metabolism necessary for healthy placental and fetal development.³ Unfortunately, approximately 20 percent of Canadian women of childbearing age do not meet the recommended amount of folate for pregnancy.³ Supplementation has been shown to be the most effective method for raising folate status, yielding superior results to dietary intake.³ Daily supplementation with 400 mcg of folic acid during the first trimester helps to decrease the development of NTD by approximately 50%; however, 800 mcg daily may help reduce the risk by nearly 70%.⁴

REFERENCES
1. EMD Millipore Corporation. (2015). Key benefits of Metafolin®. Retrieved from: < http://www.emdmillipore.com>.
2. Crider, KS, Yang, TP, Berry, RJ, Bailey, LB. Adv. Nutr. 2012; 3: 21-38.
3. Lamers, Y. Ann Nutr Metab. 2011; 59(1): 32-7.
4. Osterhues, A, Ali, NS, Michels, KB. Critical Reviews in Food Science and Nutrition. 2013; 53: 1180-1190.